CLiCk, Speak is an open source, freely available extension for the Firefox web browser. It is part of the CLC-4-TTS Suite of products, it features a mouse driven interface, and it reads web pages - hence its name. Unlike Fire Vox (http://firevox.clcworld.net) which is designed for visually impaired users, CLiCk, Speak is designed for sighted users who want text-to-speech functionality. It doesn't identify elements or announce events, two features that are very important for visually impaired users but not for sighted folks. It also has a simplified, mouse driven interface that is designed to be easy for users familiar with point-and-click graphical user interfaces. Like Fire Vox, CLiCk, Speak works on Windows, Macintosh, and Linux; and Fire Vox has multilingual support, making it great for users who are trying to learn a foreign language and need to hear foreign language web sites read out to them for practice.
If you're a sighted user who wants to have web pages read to you because you have cognitive issues (for example, dyslexia), because you have literacy issues (like me - I can understand spoken Mandarin Chinese just fine, but reading is difficult for me), because you want to reduce eyestrain and listen to a web page being read, etc., give CLiCk, Speak a try.
Click this link to learn more or to download CLiCk, Speak.